Methadone is one of the most common medical treatments for dependence on opioids, which include heroin and morphine in addition to the prescription opioid painkillers. Methadone is a long-acting drug with effects similar to the abused opiate drugs, but without the intense highs and lows. (http://www.recovery.org/topics/recovery-support-groups/)
Buprenorphine (also available combined with naloxone as Suboxone ) partially blocks the effects of other opiates if the user takes these drugs while buprenorphine is in his or her system. It is capable of producing a mild euphoria, but one with a “ceiling” effect, which means that once the drug completely occupies the opioid receptors in the brain, the user cannot achieve a greater effect by taking more of the drug. http://www.recovery.org/topics/recovery-support-groups/
CURE 